Francisco Marco Rubio’s Post

The third trial in the Asian Myeloma Network, AMN003, is our first randomised study comparing Pomalidomide, Cyclophosphamide and Dexamethasone (PCD) to Pomalidomide and Dexamethasone (PD). The all oral combination of PCD significantly improve response rates and progression free survival in a clinically meaningful way. The benefit also extend across subgroups. Listen to me talking about the results here: https://lnkd.in/gURNqeXt #mmsm #ASH23 #clinicaltrials

Efficacy and safety of intracorneal allogenic ring segment implantation in keratoconus: 1-year results Study shows that donor cornea allogenic ring segments are safe and effective. Segments can be implanted to a shallower depth of 35%, which can provide a greater impact on the surface @NacarogluSenay #Ophthalmology https://lght.ly/bn118lj

ICYMI: “I think the main takeaways is that Bendamustine is effective. It offers safe, effective lymphodepletion prior to CAR-T.” -Uttam Rao, MD, MBA #celltherapy #CART #Bendamustine #fludarabine #cyclophosphamide #Tandem24 Watch now: https://lnkd.in/eV5ZBzVn

#PancreaticCancerAwarenessMonth Transcatheter CT arteriography-guided irreversible electroporation of locally advanced pancreatic adenocarcinoma: A pictorial essay https://ow.ly/EPEV50Q5jsM

Erythrophagocytosis

Interest of early phase bone scan spect in one picture : we just don't see the same things between the two phases! 57 years old female patient, acute retrocalcaneal pain 3 months after left calcaneal Haglund's process resection early phase spect : intense activity on a retrocalcaneal collection late phase spect : limited uptake along Haglung's process resection line Total : Intensely inflammatory retrocalcaneal bursitis. Septic component is possible, subsequent leukocyte scintigraphy advised The extraosseous localization of the uptake on the early phase would have been far more challenging on a obsol... simple planar acquisition.

Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal When administered naloxone, mice treated with KAE, mitragynine, or MP under either regimen demonstrated significantly fewer signs of precipitated withdrawal than control mice that continued to receive morphine. In conclusion, while retaining some liabilities, kratom, mitragynine, and mitragynine pseudoindoxyl produced significantly less physical dependence and ameliorated precipitated withdrawal in morphine-dependent animals, suggesting some clinical value. FULL ARTICLE: https://lnkd.in/gW--Skgw Wilson LL, Chakraborty S, Eans SO, Cirino TJ, Stacy HM, Simons CA, Uprety R, Majumdar S, McLaughlin JP. Kratom Alkaloids, Natural and Semi-Synthetic, Show Less Physical Dependence and Ameliorate Opioid Withdrawal. Cell Mol Neurobiol. 2021 Jul;41(5):1131-1143. doi: 10.1007/s10571-020-01034-7. Epub 2021 Jan 12. PMID: 33433723; PMCID: PMC8164968. #kratomresearch #kratomscience #kratomstudy #kratom

Now online❗: our paper regarding the utility of interleukin-1 inhibitor -Anakinra- has shown a significant effect regarding severe outcomes related to COVID -19.. A wonderful acceptance after long list of rejections 💓.. And guys believe me DON'T QUIT! .. It'll come to you soon or later 💓 #research #clinical_research #pulmonology #Meta_analysis